New direct-acting Antivirals are changing chronic Hepatitis C treatment for the better. Hepatitis C (HCV) treatment has gone from a once exhausting 48 weeks duration to as a little as 8 weeks with a 95% sustained virologic response (SVR). SVR is defined as a viremia (the presence of viruses in the blood) 24 weeks after completion of antiviral therapy for chronic HCV infection (. In analyses of SVR durability, the incidence of late relapse is extremely low, less than 1%.